National Human Genome Research Institute Influencer
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The National Human Genome Research Institute (NHGRI) led the National Institutes of Health\'s (NIH) contribution to the International Human Genome Project, which had as its primary goal the sequencing of the human genome. This project was successfully completed in April 2003. Now, the NHGRI\'s mission has expanded to encompass a broad range of studies aimed at understanding the structure and function of the human genome and its role in health and disease.

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National Human Genome Research Institute

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1. Autism
Autism is a developmental brain disorder characterized by impaired social interactions, communication problems, and repetitive behaviors. Symptoms usually appear before the age of three. The exact cause of autism is not known, however, it is likely influenced by genetics. Autism is one of a group of related developmental disorders called autism spectrum disorders (ASDs). Other ASDs include Asperger syndrome and Rett syndrome.
2. Genetic Engineering
Genetic engineering is the process of using recombinant DNA (rDNA) technology to alter the genetic makeup of an organism. Traditionally, humans have manipulated genomes indirectly by controlling breeding and selecting offspring with desired traits. Genetic engineering involves the direct manipulation of one or more genes. Most often, a gene from another species is added to an organism's genome to give it a desired phenotype.
3. Evolution
Evolution is the process by which organisms change over time. Mutations produce genetic variation in populations, and the environment interacts with this variation to select those individuals best adapted to their surroundings. The best-adapted individuals leave behind more offspring than less well-adapted individuals. Given enough time, one species may evolve into many others.
4. Down Syndrome
Down syndrome is a genetic disease resulting from a chromosomal abnormality. An individual with Down syndrome inherits all or part of an extra copy of Chromosome 21. Symptoms associated with the syndrome include mental retardation, distinctive facial characteristics, and increased risk for heart defects and digestive problems, which can range from mild to severe.

The risk of having a child with Down syndrome rises with the mother's age at the time of conception.
5. Cancer
Cancer is a group of diseases characterized by uncontrolled cell growth. Cancer begins when a single cell mutates, resulting in a breakdown of the normal regulatory controls that keep cell division in check. These mutations can be inherited, caused by errors in DNA replication, or result from exposure to harmful chemicals. A cancerous tumor can spread to other parts of the body and, if left untreated, be fatal.